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Literature summary extracted from

  • Treiber, N.; Schulz, G.
    Structure of 2,6-dihydroxypyridine 3-hydroxylase from a nicotine-degrading pathway (2008), J. Mol. Biol., 379, 94-104.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.13.10 His-tag, expressed in Escherichia coli Paenarthrobacter nicotinovorans

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.14.13.10
-
 Paenarthrobacter nicotinovorans

Protein Variants

EC Number Protein Variants Comment Organism
1.14.13.10 C323S mutation did not cause any relevant structural disturbance Paenarthrobacter nicotinovorans

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.13.10 2,3-dihydroxypyridine
-
 Paenarthrobacter nicotinovorans
1.14.13.10 2,6-dimethoxypyridine
-
 Paenarthrobacter nicotinovorans

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.13.10 43400
-
 2 * 43400, crystal structure Paenarthrobacter nicotinovorans
1.14.13.10 113000
-
 gel filtration Paenarthrobacter nicotinovorans

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.10 Paenarthrobacter nicotinovorans Q93NG3
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.13.10
-
 Paenarthrobacter nicotinovorans

Subunits

EC Number Subunits Comment Organism
1.14.13.10 homodimer 2 * 43400, crystal structure Paenarthrobacter nicotinovorans

Synonyms

EC Number Synonyms Comment Organism
1.14.13.10 2,6-dihydroxypyridine-3-hydroxylase
-
 Paenarthrobacter nicotinovorans

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.10 FAD
-
 Paenarthrobacter nicotinovorans